Quast, T., Tappertzhofen, B., Schild, C., Grell, J., Czeloth, N., Förster,R., Alon, R, Fraemohs, L., Dreck, K., Weber, C., Lämmermann, T., Sixt, M., Kolanus, W. (2009). Cytohesin-1 controls the Activation of RhoA Modulates Integrin-dependent Adhesion and Migration of Dendritic Cells.
Blood, epublished ahead of print, Apr 23
Loer, B., Bauer, R., Bornheim, R., Grell, J., Kremmer, E., Kolanus, W., and Hoch, M. (2008). The NHL-domain protein Wech is crucial for the integrin-cytoskeleton link.
Nat Cell Biol 10, 422-428.
Busch, A., Quast, T., Keller, S., Kolanus, W., Knolle, P., Altevogt, P., and Limmer, A. (2008). Transfer of T cell surface molecules to dendritic cells upon CD4+ T cell priming involves two distinct mechanisms.
J Immunol 181, 3965-3973.
Klotz, L., Dani, I., Edenhofer, F., Nolden, L., Evert, B., Paul, B., Kolanus, W., Klockgether, T., Knolle, P., and Diehl, L. (2007). Peroxisome proliferator-activated receptor gamma control of dendritic cell function contributes to development of CD4+ T cell anergy.
J Immunol 178, 2122-2131.
Kolanus, W. (2007). Guanine nucleotide exchange factors of the cytohesin family and their roles in signal transduction.
Immunol Rev 218, 102-113.
Hafner, M., Schmitz, A., Grune, I., Srivatsan, S. G., Paul, B., Kolanus, W., Quast, T., Kremmer, E., Bauer, I., and Famulok, M. (2006). Inhibition of cytohesins by SecinH3 leads to hepatic insulin resistance.
Nature 444, 941-944.
Shamri R, Grabovsky V, Gauguet JM, Feigelson S, Manevich E, Kolanus W, Robinson MK, Staunton DE, von Andrian UH, Alon R. Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines.
Nat Immunol. (2005), 6, 497-506.
Theis MG, Knorre A, Kellersch B, Moelleken J, Wieland F, Kolanus W, Famulok M. Discriminatory aptamer reveals serum response element transcription regulated by cytohesin-2.
Proc Natl Acad Sci U S A (2004), 101(31), 11221-11226.
Gunzer M, Weishaupt C, Hillmer A, Basoglu Y, Friedl P, Dittmar KE, Kolanus W, Varga G, Grabbe S. A spectrum of biophysical interaction modes between T cells and different antigen-presenting cells during priming in 3-D collagen and in vivo.
Blood (2004), 104(9), 2801-2809.
Witte V, Laffert B, Rosorius O, Lischka P, Blume K, Galler G, Stilper A, Willbold D, D'Aloja P, Sixt M, Kolanus J, Ott M, Kolanus W, Schuler G, Baur AS. HIV-1 Nef mimics an integrin receptor signal that recruits the polycomb group protein Eed to the plasma membrane.
Molecular Cell (2004), 13(2), 179-190.
Boehm T, Hofer S, Winklehner P, Kellersch B, Geiger C, Trockenbacher A, Neyer S, Fiegl H, Ebner S, Ivarsson L, Schneider R, Kremmer E, Heufler C, Kolanus W. Attenuation of cell adhesion in lymphocytes is regulated by CYTIP, a protein which mediates signal complex sequestration.
EMBO J. (2003), 22, 1014-1024.
Tcherkasowa AE, Adam-Klages S, Kruse ML, Wiegmann K, Mathieu S, Kolanus W, Krönke M, Adam D. Interaction with the WD Motif-Containing Protein FAN Identifies Receptor for Activated C-Kinase (RACK)1 as a Novel Component of the Signaling Pathways of the p55 TNF Receptor.
J. Immunology (2002), 169, 5161-5170.
Mazerolles F, Barbat C, Trucy M, Kolanus W, Fischer A. Down-Regulation of LFA-1-dependent adhesion, induced by CD4 ligands, is associated with the formation of different multi-protein complexes.
J. Biol. Chem. (2002), 277, 1276-1283.
Weber C, Weber KSC, Nagel W, Dierks H, Kolanus W. Cytohesin-1 mediates chemokine-induced LFA-1 functions in leukocyte recruitment: linking shear-resistant arrest and directional transmigration.
Curr. Biol. (2001), 11, 1969-1974.
Kliche S, Nagel W, Atzler C, Koszinowski U, Kolanus W, Haas J. Cellular Transformation by Human Herpesvirus 8 (HHV-8) Kaposin A is mediated through membrane recruitment of Cytohesin-1.
Molecular Cell (2001), 7, 833-843.
Mayer G, Knorr T, Zehetmeier C, Kolanus W, Famulok M. Specific RNA-aptamer based inhibition of cytohesin-family guanine-nucleotide exchange factors for ADP-ribosylation factors.
Proc. Natl. Acad. Sci. USA (2001), 98, 4961-4966.
Gawaz M, Besta F, Knorr T, Kolanus W. Differential regulation of cell surface expression and internalization of the beta- 3 integrin A isoform by the beta- 3-endonexin pathway.
J. Cell Science (2001), 114, 1101-1113.
Zeitlmann L, Sirim P, Kremmer E, Kolanus W. Cloning of ACP33 as a novel intracellular ligand of CD4.
J. Biol. Chem . (2001), 276, 9123-9132.
Sirim P, Zeitlmann L, Kellersch B, Falk C, Schendel D, Kolanus W. Calcium signaling through the beta 2-cytoplasmic domain of LFA-1 requires intracellular elements of the T cell receptor complex.
J. Biol Chem. (2001), 276, 42945-42956.
Dierks H, Kolanus J, Kolanus W. Association of cytohesin-1 with the cytoskeleton is regulated by specific phosphorylation events.
J. Biol. Chem. (2001), 276, 37472-81.
Geiger C, Nagel W, Knorr T, Dierks H, Boehm T, Kremmer E, Kolanus W. Cytohesin-1 regulates beta-2 integrin mediated cell adhesion through both ARF-GEF function and direct interaction with LFA-1.
EMBO J. (2000), 19, 2525-2536.
Blind M, Kolanus W, Famulok M. Inside-out signal transduction of a leukocyte integrin modulated by cytoplasmic expression of RNA aptamers.
Proc. Natl. Acad. Sci. USA (1999), 96, 3606-3610.